STK24 and hepatocellular carcinoma: Here, we investigated whether pharmacologic inhibition of MST3 could attenuate the initiation and progression of MASH-associated HCC in vivo.<h4>Methods</h4>The therapeutic potential of MST3 inhibition was evaluated in a mouse model in which MASH-HCC was induced by a single diethylnitrosamine injection followed by 30 weeks of Western-style diet feeding.