Intestinal inflammation of rTsSPc-immunized mice was also significantly alleviated, as demonstrated that goblet cell numbers were obviously decreased, expression level of mucins (Muc2 and Muc5ac) and pro-inflammatory cytokines (IL-6 and TNF-α) was evidently declined, while expression level of anti-inflammatory cytokines (IL-10 and TGF-β) was distinctly increased after infection. Here, TNF is linked to inflammation.