Temporal expression dynamics were modeled with the multiclassPairs package in R using GSE154377.<h4>Results</h4>Consistent downregulation of four critical MRGs-MUL1, PINK1, TOMM7, and ATF4-was observed in GDM placental tissue (GSE154414) and in both placental tissue and fetal umbilical cord blood (GSE203346) but not in maternal peripheral blood. This evidence concerns the gene PINK1 and gestational diabetes.