USP10 and hepatocellular carcinoma: Co-immunoprecipitation (Co-IP), Western blotting, and immunofluorescence were used to investigate the FAM188B-Ubiquitin-specific peptidase 10 (USP10)-Yes-associated protein/Transcriptional coactivator with PDZ-binding motif (YAP/TAZ) interaction.<h4>Results</h4>FAM188B was found highly expressed in HCC cells and associated with poor prognosis.