FZD3 and small cell lung carcinoma: This study integrates bioinformatics with experimental validation to characterize the role of Frizzled-3 (FZD3), a Wnt receptor, in SCLC progression.<h4>Methods</h4>We analyzed transcriptomic data from 102 SCLC and 55 normal lung tissues retrieved from the Gene Expression Omnibus (datasets GSE6044, GSE40275, and GSE60052).