The aim of this study was to evaluate the association of FTO gene rs9939609 and rs17817449 polymorphisms with insulin resistance, some cardiometabolic parameters, and body mass index (BMI) in Turkish children with obesity.<h4>Methods</h4>The cross-sectional observational study included 83 children with obesity genotyped for variants of the FTO gene (rs9939609 and rs17817449). Here, FTO is linked to obesity due to melanocortin 4 receptor deficiency.