EGFR and acute respiratory distress syndrome: Molecular docking and molecular dynamics simulations further confirmed the stable binding and strong affinity between DG and EGFR, supporting a regulatory mechanism in the context of ARDS pathogenesis.<h4>Discussion</h4>In conclusion, DG alleviates ARDS-associated inflammation and oxidative stress through coordinated modulation of multiple signaling pathways, providing a theoretical and experimental foundation for its potential development as a natural therapeutic agent against ARDS.