C16:0-Cer exhibited a predictive value with an area under curve of 0.725, sensitivity of 74.0%, and specificity of 61.2% for SAP.<h4>Conclusion</h4>Plasma C16:0-Cer, C18:0-Cer, and CERT1 scores were significantly elevated in patients with AIS and SAP. Here, CERT1 is linked to androgen insensitivity syndrome.