<h4>Objectives</h4>The aim of this study was to explore the predictive value of the C-reactive protein-to-body mass index ratio (CBR) in the prognosis of all-cause mortality in patients with heart failure (HF) with different ejection fractions.<h4>Methods</h4>We included 1196 HF patients from the First Affiliated Hospital of Kunming Medical University after exclusion criteria. This evidence concerns the gene CRP and hydrops fetalis.