PRKAG2 and cardiomyopathy: Statistical significance was set at p < 0.05 for all analyses.<h4>Results</h4>PRKAG2 cardiomyopathy hearts exhibited significant cardiomyocyte enlargement, normal-appearing mitochondria, extensive vacuolization of most myofibers, minimal interstitial fibrosis (only two patients had mild fibrosis), and no inflammatory cell infiltration.