F2 and hereditary elliptocytosis: Exploratory ROI analysis of the globus pallidus (GP)-a region known for manganese deposition but showing no significant group-level differences in this study- revealed that, the NDI of the right GP showed positive correlations with indirect bilirubin and prothrombin international normalized ratio (all uncorrected <i>p</i> < 0.05), while the ODI of the left GP positively correlated with hemoglobin concentration (uncorrected <i>p</i> = 0.046).<h4>Conclusion</h4>NODDI reveals extensive microstructural alterations consistent with reduced neurite density index and cerebellar disorganization in HE.