Secondary outcomes were coagulation biomarkers (VWF [von Willebrand Factor], FVIII [factor VIII], fibrinogen, antithrombin III, and protein C) in relation to infection characteristics.<h4>Results</h4>Among 537 matched pairs, infections in the preceding week were associated with 2.6-fold higher CIS odds (odds ratio, 2.64 [95% CI, 1.34-5.20]) after multivariable adjustment. The gene discussed is F8; the disease is infection.