ALKBH5 and acute respiratory distress syndrome: The therapeutic potential of ALKBH5 downregulation was validated in an LPS-induced murine ARDS model through lung histology, cytokine analysis (ELISA), and microvascular permeability assessments.<h4>Results</h4>ALKBH5 was found to be a critical regulator of m<sup>6</sup>A methylation in alveolar macrophages.