INS and cystic fibrosis: This study aimed to assess the effect of ETI on beta-cell function and insulin sensitivity in people with CF (pwCF) without a history of CFRD.<h4>Methods</h4>We conducted a prospective study involving pwCF who underwent oral glucose tolerance tests (OGTT) at baseline (prior to ETI initiation) and at 6 and 18 months after starting ETI therapy.