MKI67 and neoplasm: Parameter <i>c</i> was positively correlated with the tumor size (<i>r </i>= 0.59, <i>P </i>< 0.001) and Ki67 index (<i>r </i>= 0.44, <i>P </i>< 0.001), and was notably higher in lesions with distant or regional lymph node metastases than in those without metastases.