Bioinformatic analysis of microarray datasets led to the identification of 10 female-specific hub genes, SLC4A1, THBS1, ITGB3, IL7R, CCR7, SNCA, CTNNB1, SELP, GZMK, and ITGA2B, from DEGs between control and PAH samples in females. Here, ITGB3 is linked to pulmonary arterial hypertension.