He complained of mild paresthesia of the hands and eyelid twitching but had no family history of endocrine disorders and exhibited no phenotypic features of Albright hereditary osteodystrophy.<h4>Diagnoses</h4>Laboratory evaluation revealed persistent hypocalcemia (serum calcium 7.7 mg/dL) and markedly elevated PTH levels (284.2 pg/mL) despite correction of magnesium and vitamin D insufficiency. The gene discussed is PTH; the disease is endocrine system disorder.