Both total tau (<i>P</i> = 0.006, Wilcoxon rank-sum test) and NfL (<i>P</i> = 0.044, Wilcoxon rank-sum test) levels were significantly higher in patients with suspected sepsis as compared to controls, with no significant differences in levels of GFAP or ubiquitin C-terminal hydrolase L1. The gene discussed is UCHL1; the disease is Sepsis.