IL6 and type 2 diabetes mellitus: Additionally, 25(OH) D had a negative correlation with CRP (r=-0.102, P= 0.052), IL-6 (r=-0.115, P= 0.028), and the SII (r=-0.141, P=0.007).<h4>Conclusions</h4>Compared with those in patients with T2DM microvascular lesions, the levels of the inflammatory factors CRP and IL-6 and the SII in the serum of patients with T2DM macrovascular lesions are greater, and the level of 25(OH) D is lower.