The diagnostic effect of MAIT+ combined with hs-CRP IL-ip, and IL-6 on CRS was analyzed using ROC curves.<h4>Results</h4>Both CRSsNP and CRSwNP patients exhibited significantly reduced MAIT+ frequencies compared to controls (P&lt; 0.05), with CRSwNP showing the most pronounced decrease (P &lt; 0.0 5). This evidence concerns the gene IL6 and congenital rubella syndrome.