IDH1 and central nervous system cancer: On the other hand, LMR <i>negatively</i> correlated with PLR (p = 0.00001), mitotic activity (p = 0.00001), Ki-67 LI (p = 0.001), and IDH1 mutation (p = 0.04).<h4>Conclusion</h4>Our results suggest a link between systemic inflammation and histopathology, and higher NLR and/or lower LMR may be a novel prognostic marker in gliomas.