Secondary endpoints included palpitation frequency and duration, echocardiographic evaluation of cardiac structure and function, N-terminal pro-B-type natriuretic peptide (NT-pro BNP)levels, Hamilton Anxiety (HAMA) and Depression (HAMD) Scales, and the 36-item Short-Form Health Survey (SF-36) from baseline to week 4. Here, NPPB is linked to Anxiety.