NLRP3 and acute respiratory distress syndrome: Finally, molecular docking confirmed that both catechin and procyanidin B1 exhibit strong binding affinities with NLRP3, providing a molecular basis for their targeted inhibition of the NLRP3 inflammasome.<h4>Conclusion</h4>SYQ flavonoids alleviate ALI by specifically inhibiting the NLRP3 inflammasome, providing a mechanistic basis for its traditional use in lung inflammation.