The model's performance was assessed by the area under the curve (AUC), calibration curves, and decision curve analysis (DCA).<h4>Results</h4>Multivariable analysis confirmed four independent predictors for the primary endpoint (prolonged grade 3/4 neutropenia >28 days): high tumor burden (<i>p</i> = 0.013), ferritin (<i>p</i> = 0.002), interferon-γ (IFN-γ, <i>p</i> = 0.018), and CONUT score (<i>p</i> = 0.011). Here, IFNG is linked to neutropenia.