Nonparametric Kruskal-Wallis analysis of variance with <i>post-hoc</i> Dunn's test with Bonferroni modification of significance level was used for statistical analysis.<h4>Results</h4>Under unstimulated conditions we found these significant differences:1) Higher IL-17A and TNF-α in dupilumab-treated AD patients vs. healthy controls, suggesting residual Th17 and pro-inflammatory activity despite Th2 blockade. The gene discussed is IL17A; the disease is Alzheimer disease.