IL6 and Cognitive impairment: Associations between inflammatory factors and cognition were examined using adjusted regression models.<h4>Results</h4>A doubling of IL-6 between admission and 6-9 months was associated with cognitive impairment at 18-21 months (odds ratio [OR] = 8.16; 95% confidence interval [CI] 1.82-47.26; p = 0.01), while each one-unit IL-6 increase was linked to a 1.5-point decrease in memory Z-scores (β = -1.50; 95% CI -2.57-0.43; p = 0.007).