This study aimed to evaluate the predictive efficiency of three routinely measured biochemical markers - C-reactive protein (CRP), white blood cell count (WBC), and total cholesterol (TC) - in identifying patients at risk for postoperative dry eye syndrome.<h4>Methods</h4>A total of 87 patients undergoing phacoemulsification between January 2024 and February 2025 were enrolled and categorized into dry eye (n=49) and non-dry eye (n=38) groups. This evidence concerns the gene CRP and Keratoconjunctivitis sicca.