Serum NT-proBNP hs-CRP and IL-6 concentrations were quantified by enzyme-linked immunosorbent assay (ELISA), while chest computed tomography(CT) manifestations were evaluated using the AcuteExacerbation of Idiopathic Pulmonary Fibrosis (AE-IPF)scoring system. The gene discussed is NPPB; the disease is idiopathic pulmonary fibrosis.