Multivariate analysis identified the elevation ofthese biomarkers as independent predictors of mortality inSCAP patients (P&lt; 0.01).<h4>Conclusions</h4>NT-proBNP hs-CRP and IL-6 play pivotal rolesin promoting SCAP progression by driving inflammatorycascades and pulmonary tissue injury. The gene discussed is CRP; the disease is syringocystadenoma papilliferum.