Ultimately, a predictive model for gallstones combined with occult choledocholithiasis was constructed.<h4>Results</h4>Multivariate logistic regression analysis revealed that age, alanine aminotransferase (ALT), gamma-glutamyl transferase (GGT), direct bilirubin (DBIL), location of gallstones, and ultrasonographic indication of common bile duct dilation are independent risk factors for gallstones combined with occult choledocholithiasis. This evidence concerns the gene GPT and gallstones.