TNF-a levels showed a non-significant upward trend (P= 0.058), while cortisol levels were similar between groups (P= 0.073).<h4>Conclusions</h4>Selecting NACT-IDS for advanced OC patients with hypoalbuminemia may help reduce the incidence of postoperative complications and improve the likelihood of achieving optimal cytoreduction. Here, TNF is linked to Hypoalbuminemia.