Conversely, higher expression of IL-2, IFN-g, and LIF was significantly associated with better long-term survival outcomes relative to patients with reduced expression levels (P &lt; 0.05).<h4>Conclusions</h4>The abnormal levels of IL-4, IL-17A, TNF-a, IFNg and LIF in patients with acute myeloid leukemia are increased, while the abnormal levels of IL-2, IFNg and LIF are decreased, which has certain guiding effect on prognosis assessment and can be used as auxiliary indicators for prognosis assessment of AML. The gene discussed is IL17A; the disease is acute myeloid leukemia.