To further evaluate the diagnostic value, the receiver operating characteristic (ROC) curve was employed to analyse the ability of CXCL8, tumour marker and combined colour Doppler ultrasound blood flow richness grade (Adler grade) to assess ALNM in BC patients.<h4>Results</h4>Serum CXCL8 carcinoembryonic antigen (CEA), carbohydrate antigen (CA) 153, and CA27.29 were higher in BC patients than in controls (P&lt; 0.05). The gene discussed is CXCL8; the disease is breast cancer.