COMP and pseudoachondroplasia: Compared with EDM1, PSACH manifested earlier age of onset (<i>p</i> < 0.001), shorter stature (<i>p</i> < 0.001), higher rates of lower limb deformity (<i>p</i> < 0.001), joint laxity (<i>p</i> = 0.041), anterior beaking of the vertebra and irregular/flared metaphysis (<i>p</i> < 0.001), while lower rate of joint pain/osteoarthritis (<i>p</i> < 0.001) and abnormal femoral head (<i>p</i> = 0.008).