PLA2G7 and Dilatation of the cerebral artery: The combined biomarker model showed high apparent discrimination (AUC = 0.969) and was internally validated using bootstrap resampling; however, given the small, single-center sample and the lack of adjustment for key clinical and morphological predictors, the model requires cautious interpretation and independent validation.<h4>Conclusion</h4>PLR, Lp-PLA2, MHR, SII, and HCY were associated with rupture status in small to medium-sized intracranial aneurysms.