Through univariate and multivariate Cox proportional hazards regression analyses, we found that the high expression of Bcl-2-interacting mediator of cell death (<i>BCL2L11</i> [<i>BIM</i>]) and phorbol-12-myristate-13-acetate-induced protein 1 (<i>PMAIP1</i> [<i>NOXA</i>]) in NK cells is associated with poorer survival across various cancer types. The gene discussed is PMAIP1; the disease is cancer.