Liver enzymes, noninvasive liver fibrosis scores and liver function tests showed additive effects across metHC, AUD and metAUD compared to HC, with the largest effects in metAUD for GGT, AST, ALT, CRP, albumin, direct bilirubin, FIB-4, LiverRisk and NFS (p < 0.001). This evidence concerns the gene ALB and Hepatic fibrosis.