After glucocorticoid therapy, the body temperatures of these children normalized, and the follow-up routine blood test, CRP, and ESR results gradually returned to the respective normal ranges.<h4>Conclusion</h4>These findings highlight that MOG antibody-associated aseptic meningitis primarily manifests as prolonged fever, with peripheral inflammatory markers that mimic a severe bacterial infection, while CSF profiles resemble those of viral encephalitis. The gene discussed is CRP; the disease is aseptic meningitis.