PTPRC and breast cancer: We evaluated a CTC-based assay as a complementary biomarker for breast cancer detection in an Asian population with a high prevalence of dense breast tissue.<h4>Methods</h4>In this single-center, prospective, blinded study, peripheral blood from Taiwanese women with breast cancer and healthy controls was analyzed using a CTC-enumeration platform (CMx) based on biomarker expression (cytokeratin 18 [CK18], mammaglobin [MGB], CD45), cell morphometry, and nuclear features.