Prognostic heterogeneity across international normalized ratio (INR)-based strata was examined.<h4>Results</h4>The final prediction model incorporated eight significant predictors: age (OR 1.051, 95% CI 1.033-1.070), INR (OR 1.423, 95%CI 1.231-1.644), creatinine (OR 1.171, 95%CI 1.071-1.208), platelets (OR 0.995, 95%CI 0.993-0.997), white blood cell (OR 1.116, 95%CI 1.078-1.155), total bilirubin (OR 1.027, 95%CI 1.002-1.052), peptic ulcer (OR 0.336, 95%CI 0.134-0.845), and Aspartate Aminotransferase/Alanine Aminotransferase (AST/ALT) (OR 1.508, 95%CI 1.294-1.757). The gene discussed is GPT; the disease is peptic ulcer disease.