The Shapley Additive explanation (SHAP) values provided model interpretability.<h4>Results</h4>The Boruta algorithm selected six features: New York Heart Association (NYHA) classification, cardiac troponin T (cTnT), prothrombin time (PT), depression severity, abdominal circumference, and diastolic blood pressure (DBP). The gene discussed is TNNT2; the disease is depressive disorder.