Hence, delving into the molecular mechanisms contributing to GC advancement, and discovering innovative therapeutic targets and latent biomarkers for GC remain at the forefront of research.<h4>Methodology</h4>QRT-PCR and western blot procedures were followed to make clear the targeting protein for Xklp2 (TPX2) expression in GC and surrounding non-tumor tissues. The gene discussed is TPX2; the disease is gastric cancer.