<h4>Purpose</h4>To investigate the value of T1 mapping and intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) quantitative parameters in predicting PD-L1 expression and dynamically monitoring immunotherapy efficacy in advanced lung cancer.<h4>Materials and methods</h4>23 patients pathologically diagnosed with advanced lung cancer were collected. Here, CD274 is linked to lung carcinoma.