VEGFA and polycystic ovary syndrome: Statistical analyses were performed using t-test and one-way or two-way ANOVA followed by appropriate <i>post-hoc</i> tests (p < 0.05).<h4>Results</h4>Single-cell transcriptomic analysis revealed intrinsic differences in cell cycle process, vascular endothelial growth factor (VEGF) signaling, apoptosis, and androgen signaling in PCOS iPSC-derived ECs.