GNAI1 and Anxiety: Next, to investigate the impact of PBN(CGRP) inhibition on anxiety-like behavior following chronic intermittent ethanol vapor exposure (CIE), <i>Calca</i> <sup>CRE</sup> female and male mice expressing CRE-dependent hM4D (Gi) DREADDs in the PBN were tested in EPM during acute withdrawal.