IL6 and bacterial infectious disease: A diagnosis model combined IL-10, platelet and IFN-γ/IL-6 ratio was built, and the AUC was 0.95, with the sensitivity and specificity as 90.3% and 89.6%, respectively.<h4>Conclusions</h4>The IFN-γ/IL-6 ratio during febrile episodes may be useful in the early diagnosis of PFAPA by differentiating this disease from bacterial infection.