The purpose of this proof-of- concept study was to examine whether IL-8 could act as an efficacious biomarker for UTI infection in combination with confirmed bacterial infection.<h4>Methods</h4>In this study, IL-8 levels were measured in anonymised urine samples sent to the pathology laboratory for microbiology testing using commercially available ELISA kits. Here, CXCL8 is linked to bacterial infectious disease.