METHODS: We conducted a comprehensive bioinformatic analysis of PDZK1IP1 using publicly available platforms (TIMER, GEPIA, c-BioPortal, TISIDB, SangerBox) to examine its expression, diagnostic potential, prognostic relevance, and correlation with key immune features, including immune checkpoint genes, tumor mutational burden, neoantigen load, tumor stemness, and immune cell infiltration. Here, PDZK1IP1 is linked to neoplasm.