Although the pituitary adenoma was initially suspected to be a prolactinoma and treated with cabergoline, insufficient tumor size reduction after 1 year of therapy led to revision of the diagnosis to a nonfunctioning pituitary neuroendocrine tumor.<h4>Lessons</h4>This case underscores the importance of considering MEN1 even in elderly patients with atypical manifestations, emphasizes the value of integrating prior medical history into diagnosis, and suggests a potential role of rs2959656 in MEN1 pathogenesis. Here, MEN1 is linked to neoplasm.