LMTK2 and rheumatoid arthritis: The results were validated in cohort of 45 patients with RA, divided into a high disease activity group (HDA; DAS28 > 5.1; n = 22) and a non-high disease activity group (non-HDA; DAS28 ≤ 5.1; n = 23) along with 24 control subjects, using quantitative PCR (qPCR).<h4>Results</h4>LMTK2 LINOUT expression correlated negatively with disease activity (rs  = -0.30) and distinguished RF-negative patients (n = 17) from HCs (p = 0.027).