On contrast-enhanced MRI, ring-enhancing lesions were more frequently observed in the edematous group (76.8%), compared to the non-edematous group (25%).<h4>Conclusion</h4>In patients with hematogenous disseminated pulmonary tuberculosis and concurrent intracranial tuberculomas, higher peripheral CD4 + T-lymphocyte counts are independently associated with the presence of perilesional edema and a greater likelihood of ring-like enhancement on MRI. This evidence concerns the gene CD4 and central nervous system tuberculosis.